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Carole Caranta

Carole Caranta

INRA, Research director

Chef  de Département  (par interim) de Génétique et Amélioration des Plantes de l'INRA

Animatrice de l'équipe "Résistance aux virus" (ReV)

04 32 72 27 26


  • 2012 - Head of the Genetics and plant Breeding division (interim)
  • 2009-2011- Deputy Head of the Genetics and Plant Breeding division
  • Leader of the research group on Plant Resistance to Viruses, Research Unit “Génétique et Amélioration des Fruits et Légumes”

Education History

  • 2003 - Habilitation à diriger des recherches
  • 1995 - PhD, Université de la Méditerranée. Genetic dissection of polygenic resistance to viruses in pepper: genomic organization of resistance factors (INRA Avignon, France).
  • 1992 - Master degree in Cellular and Molecular Biology, Univ Marseille II.

Employment history

  • 2005 – Directeur de Recherche, INRA
  • 1997 – Chargé de Recherche, INRA
  • 1996 - Post-doctoral position. Cellular characterization of resistance mechanisms against potyviruses in pepper. Laboratory of Dr. F. Ponz, INIA, Spain.
  • 1992 - Attachée Scientifique Contractuelle, INRA

Scientific Skills

Plant Virus Interactions - Molecular Genetics- Genomics

Selected Publications

Author of more than 40 publications in international journals

  • Mazier, M., Flamain, F., Nicolaï, M., Sarnette, V., Caranta, C. 2011. Knock-down of both eIF4E1 and eIF4E2 confers broad spectrum resistance against potyviruses in tomato. PLoS One,6(12): e29595. doi:10.1371/journal.pone.0029595
  • Schepetilnikov, M., Kobayashi, K., Geldreich, A., Caranta, C., Robaglia, C., Keller, M., Ryabova, L.A. 2011. Viral factor TAV recruits TOR/S6K1 signalling to activate reinitiation after long ORF translation. EMBO Journal, doi:10.1038/emboj.2011.
  • Piron, F., Nicolaï, M., Minoïa, S., Piednoir, E., Moretti, A., Salgues, A., Zamir, D., Caranta, C. and Bendahmane, A. 2010. An induced mutation in tomato eIF4E leads to immunity to two potyviruses. PLoS One 5(6):e11313.
  • Arens, P., Mansilla, C., Deinum, D., Cavellini, L., Moretti, A., Rolland, S., van der Schoot, H., Calvache, D., Ponz, F., Collonnier, C., Mathis, R., Smilde, D., Caranta, C., Vosman, B. 2010. Development and evaluation of robust molecular markers linked to disease resistance in tomato for Distinctness, Uniformity and Stability testing. Theor. Appl. Genet., (DOI 10.1007/s00122.009-1183-2), 120(3):655-664.
  • Gallois, J-L., Charron, C., Sanchez F., Pagny G., Houvenaghel M-C., Moretti A., Ponz F., Revers F., Caranta, C., and German-Retana, S. 2010. A single amino acid change in the Turnip mosaic virus viral genome-linked protein (VPg) confers virulence towards A. thaliana mutants knocked-out for eukaryotic initiation factors eIF(iso)4E and eIF(iso)4G. J. Gen. Virol., 91, 288-293.
  • Rubio, M., Nicolaï, M., Caranta, C., and Palloix, A 2009. Allele mining in the pepper gene pool provided new complementation effects between pvr2-eIF4E alleles and pvr6-eIF(iso)4E for resistance to Pepper veinal mottle virus. J. Gen. Virol. 90:2808-2814..
  • Rubio, M., Caranta, C., and Palloix, A. 2008. Functional markers for selection of potyvirus resistance alleles at the pvr2-eIF4E locus in pepper using tetra-primer ARMS-PCR technology. Genome 51:767-771.
  • Charron, C., Nicolaï, M., Gallois, J.L., Robaglia, C., Moury, B., Palloix, A. and Caranta, C. 2008. Natural variation and functional analyses provide evidence for coevolution between plant eIF4E and potyviral VPg. The Plant Journal 54: 56-68.
  • Nicaise, V., Gallois, J.L., Chafiai, F., Allen, L.M., Schurdi-Levraud, V., Browning, K.S., Candresse, T., Caranta, C., Le Gall, O., and German-Retana, S. 2007. Coordinated and selective recruitment of eIF4E and eIF4G factors for potyvirus infection in Arabidopsis thaliana. FEBS Letters, 581:1041-1046
  • Robaglia, C., Caranta, C. 2006. Translation initiation factors: a weak link in plant RNA virus infection. Trends in Plant Science, 11(1):40-45.
  • Ruffel, S., Gallois, J.L., Moury, B., Robaglia, C., Palloix, A., Caranta, C. 2006. Simultaneous mutations in translation initiation factors eIF4E and eIF(iso)4E are required to prevent Pepper veinal mottle virus infection in pepper. J. Gen. Virol., 87:2089-2098.
  • Ayme, V., Souche, S., Caranta, C., Jacquemond, M., Palloix, A., Moury, B. Multiple mutation pathways towards virulence in a plant RNA virus. Genetics, soumis. Molecular Plant Microbe Interactions, 19(5):557-563.
  • Ruffel, S., Gallois, J.L., Lesage, M.L., Caranta, C. 2005. The potyvirus recessive resistance gene pot-1 is the tomato orthologue of the pepper pvr2-eIF4E gene. Molecular Genetics Genomics, 274:346-353.
  • Ruffel, S., Caranta, C., Palloix, A., Lefebvre, V., Caboche, M., Bendahmane, A. 2004. Structure analysis of the eukaryotic initiation factor 4E gene controlling potyvirus resistance in pepper: explotation of a BAC library. Gene, 338:209-216.
  • Parrella, G., Moretti, A., Gognalons, P., Lesage, M.L., Marchoux, G., Gebre-Selassié, K., Caranta, C. 2004. The Am gene controlling resistance to Alfalfa mosaic virus in tomato is located in the cluster of dominant resistance gene on chromosome 6. Phytopathology, 94(4):345-350.
  • Moury, B., Morel, C., Johansen, E., Guilbaud, L., Souche, S., Ayme, V., Caranta, C., Palloix, A., Jacquemond, M. 2004. Mutations in Potato virus Y genome-linked protein determine virulence towards monogenic recessive resistances in Capsicum annuum and Lycopersicon hirsutum. Mol. Plant-Microbe Interact., 17(3):322-329.
  • Nicaise, V., German-Retana, S., Sanjuan, R., Dubrana, M.P., Mazier, M., Maisonneuve B., Candresse, T., Caranta, C., Le Gall, O. 2003. The eucaryotic translation initiation factor 4E (eIF4E) controls lettuce susceptibility to the potyvirus Lettuce mosaic virus. Plant Physiology, 132(3):1272-1282.
  • Ruffel, S., Dussault, M.H., Palloix, A., Moury, B., Bendahmane, A., Robaglia, C., and Caranta, C. 2002. Natural recessive resistance gene against Potato Y potyvirus in pepper corresponds to the eucaryotic initiation factor 4E (eIF4E). The Plant Journal, 32(6)1067-1075.
  • Duprat, A., Caranta, C., Revers, F., Creff, A., Menand, B., Browning, K., and Robaglia, C. 2002. The Arabidopsis gene coding for the eucaryotic initiation factor (iso)4E is dispensable for plant growth and required for susceptibility to Turnip mosaic and Lettuce mosaic potyviruses. The Plant Journal, 32(6):927-934.
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INRA UR 1052 GAFL Rédaction : Carole Caranta
Dernière mise à jour 09/01/2012